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Ana Cruz Kayne
- Place of birth: New Haven, Connecticut, USA
Ana Kayne (born April 28, 1984) is an American actress and writer, known for her performances in Barbie (2023), Little Women (2019), Jerry & Marge Go Large (2022) and Painkiller (TV 2023). She was also in Another Earth (2011), The Creek When He Came Back (2016) and Baby Teeth (2016).
